San laban ninnu na, furakɛli tigitigi ni sɛgɛsɛgɛli fɛɛrɛ in vitro yiriwali teliya fɛ, joli-sira-funu-minɛnw, n’olu ye kɛnɛyaso sɛgɛsɛgɛli baarakɛminɛn jɔnjɔnw ye, olu bɛ ka kɛ izini in ka ɲɛmajɔ ye fɛɛrɛ kuraw siratigɛ la. K’a ta bololabaara laada sɛgɛsɛgɛli la ka taa a bila otomatiki sɛgɛsɛgɛli la min bɛ se ka kɛ kosɛbɛ, jolilabanaw furakɛcogo fɛɛrɛw seginni ma dɔrɔn ka sɛgɛsɛgɛli kɛcogo ɲɛ, nka a ye sɛgɛsɛgɛli dɛmɛ tigitigi di fana diɲɛ furakɛlitɔnw ma.
Fɛɛrɛko siratigɛ la, immunoturbidimetry, flow cytometry ani molecular biology fɛɛrɛw kɛra joli-sira-funu-minɛnw ɲɛminɛcogo kunbaba ye. Ni an ye immunoturbidimetry ta misali la, a bɛ farikolojɔli dumuni kɛrɛnkɛrɛnnenw kɔnɔfɛnw dɔn antigène-anticorps reaction fɛ, wa a bɛ baara kɛ kosɛbɛ banaw sɛgɛsɛgɛli la i n’a fɔ jolidɛsɛ ni funu. Flow cytometry, n’a ka multi-parameter analysis seko ye, o kɛra baarakɛminɛn nafama ye jolidɛsɛ suguya sɔrɔli la ani farikolo tangacogo jateminɛni na. Ka fara o kan, PCR nimɔrɔ ni NGS (sequencing generation nata) fɛɛrɛw donna sen kan, o ye joli kuruw joginda misɛnnin tolenw kɔlɔsili kɛ fɛn ye min bɛ se ka kɛ kosɛbɛ, o bɛ kɛ sababu ye ka kunnafoniw dɛmɛ furakɛli la min bɛ kɛ mɔgɔ kelen-kelen bɛɛ ye.
Suguw ka ɲinini bonya ye joli-sira-funu-kɛcogo caman yiriwali sabati. Sisan, fɛnɲɛnamafagalanw ye baara caman kɛ i n’a fɔ joli kɛcogo, joli segincogo, biyokimiki taamasiɲɛw ani banaw sɛgɛsɛgɛli jamu fɛ. Olu cɛma, point-of-care testing (POCT) reagents bɛ ɲini kosɛbɛ ladonni fɔlɔ ni kɔrɔtɔko la k’a sababu kɛ u tacogo ye ani u ka jaabi teliya. O waati kelen na, sɛgɛsɛgɛli kɛcogo otomatikiw ka diyabɔli fana ye reagent dilannikɛlaw wajibiya ka formula sabatili ɲɛ walasa ka ladamu baarakɛminɛnw baarakɛcogo wajibiyalenw ma minnu bɛ se ka baara kɛ kosɛbɛ.
A ka kan ka kɔlɔsi ko diɲɛ sariyaw ka gɛlɛyaw gɛlɛyali bɛ ka izini sariyaw sɛmɛntiya kokura. EU ka IVDR sariyaw ni Ameriki FDA ka laadilikan labanw fila bɛɛ bɛ sinsin fɛnɲɛnamafagalanw ka ɲɛnamaya kɛcogo bɛɛ lajɛlen ɲɛnabɔli kan, i n’a fɔ fɛnɲɛnamafagalanw nɔfɛtaama, u dilanni taabolo jogoɲini, ani kɛnɛyaso tiɲɛni kunnafoniw dafalen. O kɛra sababu ye ka tɔnw bila ka dɔ fara u ka ɲinini ni yiriwali musakaw kan walasa ka reagentw ka batch-to{3}}batch control sekow yiriwa ka taa a fɛ ka sɔrɔ ka sɛgɛsɛgɛli ni kɛrɛnkɛrɛnnenya sabati.
Don nataw la, ni hakililata ni kunnafonidilanba fɛɛrɛw faralen don ɲɔgɔn kan, jolilabanaw bɛ se ka yiriwa hakili siratigɛ la. Misali la, sɛgɛsɛgɛli paramɛtɛrɛw ɲɛnabɔli masin kalanni algorisimuw fɛ, walima ka calibration systems adaptatives labɛn walasa ka hadamadenw ka dɛmɛ dɔgɔya. Nin ko kura ninnu bɛna jolilabanaw jɔyɔrɔba sabati ka taa a fɛ in vitro sɛgɛsɛgɛli siratigɛ la ani ka fɛɛrɛ ɲumanw di diɲɛ kɛnɛyako ma.